# \#saa
**URL:** https://rcop.michaeljfox.org/tag/saa/75.md
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## [What does a negative alpha-synuclein SAA result mean in a Parkinson's patient?](https://rcop.michaeljfox.org/t/what-does-a-negative-alpha-synuclein-saa-result-mean-in-a-parkinsons-patient/1470)
**Author:** [@AmgadDroby](https://rcop.michaeljfox.org/u/AmgadDroby)\
**Replies:** 1\
**Last updated:** [March 17, 2026, 5:12am UTC](https://rcop.michaeljfox.org/t/what-does-a-negative-alpha-synuclein-saa-result-mean-in-a-parkinsons-patient/1470 "2026-03-17T05:12:34Z")
A new study from the PPMI cohort (Brooker et al., Movement Disorders 2026; https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.70197) looked systematically at the ~10% of sporadic PD patients who test negat…
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## [SAA data in PPMI - data overview video](https://rcop.michaeljfox.org/t/saa-data-in-ppmi-data-overview-video/452)
**Author:** [@jodiefm](https://rcop.michaeljfox.org/u/jodiefm)\
**Replies:** 0\
**Last updated:** [June 12, 2024, 4:33pm UTC](https://rcop.michaeljfox.org/t/saa-data-in-ppmi-data-overview-video/452 "2024-06-12T16:33:47Z")
For anyone interested in understanding and using the Seed Amplification Assay (SAA) data in PPMI, I recently recorded a 6 minute overview video in conjunction with the MJFF data resources team. You can download it from …
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## [Plasma Biomarkers in Fox Insight](https://rcop.michaeljfox.org/t/plasma-biomarkers-in-fox-insight/141)
**Author:** [@malosco](https://rcop.michaeljfox.org/u/malosco)\
**Replies:** 12\
**Last updated:** [November 14, 2023, 10:40pm UTC](https://rcop.michaeljfox.org/t/plasma-biomarkers-in-fox-insight/141 "2023-11-14T22:40:43Z")
Hi everyone, There are three purposes to this post: (1) identify collaborators to brain storm projects on the usefulness and validation of plasma biomarkers (e.g., alpha synuclein) for the detection of PD, (2) understan…