Hi All, I’m Fanny Elahi, a physician-scientist and Associate Professor of Neurology, Neuroscience, Pathology, and Molecular and Cell-Based Medicine at the Icahn School of Medicine at Mount Sinai. I completed residency in neurology, and fellowship in neurodegenerative disorders with clinical and basic science training.
My lab uses multi-modal models with a big focus on biospecimen omics and molecular biomarkers to identify therapeutic targets in neurodegenerative diseases. Our scientific questions pertain to the role of vascular pathologies in brain degeneration and dementia. We are proteinopathy agnostic. But the genetic models we study have strong parkinsonian phenotypes. We take a multidisciplinary approach combining clinical, cellular, and molecular phenotyping to model disease and find vascular therapeutic targets. Analyses are based on human tissue and biospecimen for discovery of molecular dysregulations and modeling mechanisms in iPSC-derived in vitro models. Much of the work underway is centered on genetic risk for degenerative brain disorders, such as NOTCH3 mutations and APOE4. Here’s my lab’s website: elahilab.com
I look forward to working with you all! I can contribute expertise in molecular biomarkers and multi-modal models of disease.