What are you currently working on? Let us all know!

Hello everyone. I would love to get to know you a bit better. We often focus on datasets, analyses, and data sharing, and it is easy to forget what drives those discussions, which is: what are we studying? Even a brief exchange could spark ideas, collaborations, questions, suggestions that help our colleagues and bring us closer as a community.

I will start. Like many of you, I am not working on only one project and two main topics are currently on my desk.

  1. Epidemiology: I am analyzing the LARGE-PD dataset to identify environmental risk factors for PD and to estimate their Population Attributable Fractions. To my knowledge, few studies in our field have applied this epidemiological framing to such data.
  2. Subtyping: My PhD focuses on identifying PD subtypes using biological data genomics, transcriptomics, and neuroimaging across PPMI, PDBP, and STEADY-PD III. Our preliminary results show that genetic information can delineate reproducible PD subtypes associated with distinct longitudinal progression across cohorts. The next step is to write the manuscript which, as you all know, can be the hardest part.

And you, my fellow colleagues. Tell us a bit about what you are working on!

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oiiiiiiiiiiiiiiiiiiiiiiii! i’m all over the place and felt ashamed looking at your lovely organized post!!! i work on sex and gender differences for risk, clinical profile, progression, daily impact, and pathology in Parkinsonian disorders in a nutshell. ever since i found the Lewy body dementia (LBD) community, i’ve taken a bit of a break from Parkinson’s disease, but now i’m bouncing back to it for data collection. i also came across opportunities for atypical Parkinsonians like progressive supranuclear palsy, corticobasal degeneration, multiple system atrophy, so i’ve been working on those too. basically anything sprinkled with underrepresented groups that i can understand the data for, i’ll be intrigued :slight_smile: i have veeeeery basic coding skills so i can’t really dive into the genomics and all, but i get to work with fabulous people that can do such analyses so i can at least read and understand the notebooks and can translate those into the papers.

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Hi! I’ve missed this post for a while! @danieltds I’m also working on PD molecular subtypes - wondering whether you’d like to setup a call some time to discuss potential interesting overlaps? :slight_smile: