Best analyses to combine PD data with other neurodegenerative disease data

With interest in comparing PD sample data to sample data from other neurodegenerative diseases, what is the best way to combine these data sets for analysis to identify common and divergent disease dysregulation/pathways?

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It would be Great to try to find the gap betwwen some distases with Parkinsonism and ataxia. For example SCA 2 and 3, and RFC1

At genetic level, you could do GWAS-Pairwise and LDSR analysis. At expression level, maybe you could do differential expression analysis? I am not sure at metabolic level tho.