BRAIN BASIC FUNCTIONAL CIRCUIT. THE FUNCTIONAL UNIT OF THE BRAIN.ABSTRACT.pdf (64.0 KB)
This is the abstract of one writing I am trying to built about the functional unit of the brain which is a very hard topic, so I would like that somebody in the Community can give a glance and say something that helps me to persist in this work. I will be very grateful por any word that I get.
Hi @rehcraeser, thanks for sharing this post. Would you be able to elaborate a bit on this abstract? In particular, given the scope of this community, could you speak to how this work relates to Parkinson’s disease specifically and/or neurodegenerative diseases in general?
Hello Greg,
Thank you very much for you interesting message. I hope you are doing well. Since witnessing so many failures in addressing illnesses, while working as a professor in a hospital, I thought, “Something is missing here, or something is wrong.” So I began to think about pathology, and I discovered that there is a type of pathology that arises from quantitative changes in the function of organs such as glands, muscles, and others. If these changes are produced by innervation, that is, by the nervous system, then excitatory, inhibitory, and peripheral neurons must be positioned in relation to one another, forming a trio, such that when the excitatory neuron predominates, the organ’s function increases, and when the inhibitory neuron predominates, the organ’s function decreases. Thus, I believe I have identified the functional unit of the nervous system, and the alteration in the temporal balance of the release of the two classes of neurotransmitters is the initiation of the pathology. Since one form of Parkinson’s disease is characterized by muscle rigidity, I have thought that this is due to a predominance of the excitatory neuron, and the form that presents with tremor is due to a failure of that excitatory neuron.
Another point is that the known voltage of a neuron receiving innervation becomes less negative, from -65 mV to -55 mV when it is excited, and from -75 mV when it is inhibited. This behavior generates a binary code: one bit, ONE and ZERO. In other words, the nervous system is a mixed biological and electronic machine. With this functional unit, we are trying to generate different hardware components that correspond to the anatomy of the nervous system.
I leave it here and I would like to read your authorized comments.
I wish you the best time, kind regards.
Ramiro
(Attachment FUNCION GLANDULAR ALTERADA.bmp is missing)